PLACE AND DATE OF BIRTH:
Sewickley, Pennsylvania, July 3, 1950

OFFICE ADDRESS:
Alexandria Fairfax Neurology, PC
1500 N. Beauregard St. #300
Alexandria, VA 22311
(703) 845-1500

CERTIFICATION:
American Board of Internal Medicine 1976, Certificate #56112
American Board of Psychiatry and Neurology 1980, (Neurology) #20530
American Board of Electroencephalography 1984, #275
American Board of Qualification in Electroencephalography
(American Board of Clinical Neurophysiology), 1985
American Board of Sleep Medicine, 2003

LICENSURE:
Virginia 0101029506
District of Columbia #15978 (inactive)
Illinois #36-50013 (inactive)

EDUCATION:
Pennsylvania State University
Bachelor of Science with Honors, 1971

Thomas Jefferson University
Doctor of Medicine, 1973

Enrolled in a five year BS/MD program with Pennsylvania State University and Thomas Jefferson University, Jefferson Medical College, June 1968. (Completed undergraduate degree requirements and four years of medical school in five calendar years.) Studies started at Pennsylvania State University and continued through August 1969. Began medical school at Jefferson Medical College, September 1969. Returned to Pennsylvania State University the summer of 1970 and graduated in absentia from Pennsylvania State University, September 1971 with honors. Graduated from Thomas Jefferson University/Jefferson Medical College of Philadelphia, June 1973.

INTERNSHIP AND RESIDENCY:
Internship and Residency in Internal Medicine, July 1973 through December 1975
Rush Presbyterian/St. Luke's Medical Center
Chicago, Illinois
Chairman of Medicine, Theodore B. Schwartz, M. D.

Residency in Neurology, January 1976 through June 1978
Rush Presbyterian/St. Luke's Medical Center
Chairman of Neurology, Maynard Cohen, Ph.D., M. D.

HOSPITAL STAFF APPOINTMENTS:
Inova Alexandria Hospital
Alexandria, Virginia

Inova Fairfax Hospital
Falls Church, Virginia

HONORS AND AWARDS:
Phi Eta Sigma Science Honor Fraternity, 1969
Elected to Honorary Board - Epilepsy Foundation/National Capitol Area, 1990
Named in "Top Doctors" by Washingtonian Magazine, 1991-present
Named in Washington Consumer Checkbook, "Area's Outstanding Specialists", 1993-present

PROFESSIONAL SOCIETIES/ORGANIZATIONS:
American Academy of Neurology
American Academy of Sleep Medicine
American Association for the Study of Headache
American College of Physicians
American EEG Society
American Medical Association
Arlington County Medical Society
Medical Society of Northern Virginia
Medical Society of Virginia

PUBLIC SERVICE/ORGANIZATIONS:
Epilepsy Foundation
National Capitol Area
Board of Directors 1980-1989

Cosmos Club
Washington, D. C.
Member 1989-present
Planning Committee 1991 to 1995
Awards Committee 1996-1999

Epilepsy Foundation/National Capitol Area
Professional Advisory Board
Member 1985 to 1993

Washington Metropolitan Bioethics Network
Member 1991 to present

MEDICAL STAFF POSITIONS & APPOINTMENTS:
Rush Presbyterian /St. Luke's Medical Center
Instructor, Neurology 1976-1978
Instructor, Internal Medicine 1974-1976
Assistant Instructor in Internal Medicine 1973-1974

Inova Alexandria Hospital
Chairman of Medicine - Current
Chairman, Ethics Committee - Current
Chair, Ethics Committee 2000-Present
Chairman, Bylaws Committee 1997-1999
Medical Staff Representative to the AMA Organized Medical Staff Section, 1997-1999
Medical Staff Representative to the Board of Directors 1997-1998
President, Medical Staff 1995-1996
Chairman, Medical Quality Assurance Committee 1992-1994
President Elect, Medical Staff 1992-1994
Member, Bioethics Committee 1991 to present
Chief, Section of Neurology 1984-1990
Member of Executive Committee, Member at Large 1988-1989

Inova Fairfax Hospital
Chief of Neurodiagnostics - Current
Preceptor in Georgetown Psychiatry Program at Inova Fairfax Hospital 1987 to Present
Member, Stroke Committee 1988 to October 1991
Chairman, Quality Assurance for the Section of Neurology 1988-1994

Georgetown University
Clinical Assistant Professor, Department of Neurology
1991-Present

Innovation Health
Board Member 1998-2000

Inova Health System
Operation Stroke
A 5-year Regional Joint Venture between Inova Health System and the American Heart Association
Co-Chair 1999-Present

Inova Medical Affairs Council
Member 1997-2002

Inova Healthcare Ethics Council
Member 1999-Present

PUBLICATIONS/POSTER PRESENTATIONS:

Pancreatic Pseudocyst Presenting as Hemothorax: A Case Report - American Journal of Gastroenterology, 1978 69:84-87

Reversible Mental Symptoms in Temporal Arteritis - Journal of Nervous and Mental Disorders, 166:446 1978.

Calcification Basal Ganglia, Neurology March 1979.

Transient Global Amnesia Following Cerebral Arteriography: Report of Seven Cases, Archives of Neurology, February 1983.

Transient Global Amnesia Associated with Migraine. Correspondence, Neurology, February 1983.

Transient Global Amnesia Following Cerebral Arteriography. Correspondence, Archives of Neurology, April 1983.

Monosodium Glutamania: The Chinese Restaurant Syndrome Revisited, JAMA, August 17, 1984 Volume 52, No. 7

Monosodium Glutamania vs Alcohol in the Chinese Restaurant Syndrome. Correspondence, JAMA, April 5, 1985 Volume 253, No. 13

Neurologic Disease: Five Scenarios to Manage in Patient Care, May 30, 1994, 32-51

"Restless Legs Syndrome", JAMA, January 17, 1996, Volume 275, No. 3

Series of Quarterly Columns "Ask Dr. Cochran" in the Newsletter of the Epilepsy Foundation National Capitol Area The Advocate 1989-1992 (Catamenial Epilepsy, Epilepsy Surgery, Alcohol and Epilepsy, Lifestyle and Epilepsy, Generic Medicine, Monotherapy)

Chapter Entitled Clinical Electrophysiology in Patient Care in Neurosurgery, Little Brown & Company, James R. Howe, M. D. 1983.

Poster Presentation, "Depakote in Clinical Outpatient Practice...Experience of 99 Consecutive Patients" given at The Practicing Physicians' Approach to the Difficult Headache Patient, Orlando, Florida, July 1998.

Poster Presentation, "Divalproex Sodium versus Tricyclic Agents in Migraine Prophylaxis: A Clinical Study comparing Efficacy and Tolerability" given at The Practicing Physicians' Approach to the Difficult Headache Patient, Orlando, Florida, July 1999.

Poster Presentation, "Concurrent Use of Sumatriptan and Naratriptan in Migraineurs with Recurrent Headache" given at The American Headache Society Meeting, Montreal, Canada, June 2000.

Poster Presentation, "Efficacy of Topiramate in Prophylactic Treatment of Migraine Headaches With and Without Aura: Open-Label Experience" given at The Practicing Physicians' Approach to the Difficult Headache Patient, Lake Buena Vista, Florida, July 2000.

Effect of Modafinil on Fatigue Associated with Neurologic Illness, Journal of Chronic Fatigue, Vol. 8(2) 2001 65-70

Poster Presentation, "Divalproex Sodium ER: Comparison to Divalproex Sodium" presented at Diamond Headache Meeting, Orlando, Florida, July 2001.

Poster Presentation, "Oxycarbazepine in Migraine Prophylaxis: A Pilot Study" presented at Diamond Headache Meeting, Orlando, Florida, July 2001.

Poster Presentation, "Incidence of Hyponatremia: 100 Consecutive Patients Treated With Antiepileptic Drugs" presented at Diamond Headache Meeting, Orlando, Florida, July 2001.

Poster Presentation, "Efficacy of Zonisamide in the Treatment of Neuropathic Pain " presented at American Pain Society, Baltimore, Maryland, March 2002.

Poster Presentation, "Efficacy of Zonisamide in Prophylactic Treatment of Migraine Headaches with or without Aura: Open-label Experience in 7 patients" presented at American Pain Society, Baltimore, Maryland, March 2002.

Poster Presentation, "Open-Label Experience in Patients with Migraine and Facial Pain: Efficacy of Zonisamide as Prophylaxis" presented at American Headache Society Annual Meeting, Seattle, Washington, June 2002.

Poster Presentation, "Clinical Experience With Vagal Nerve Stimulation and Excessive Daytime Sleepiness as Measured by the Epworth Sleepiness Scale" presented at APSS Annual Meeting, Seattle, Washington, June 2002.

RESEARCH:

Co-investigator: pentoxifylline in acute non-hermorrhagic stroke, 1978.

Co-investigator: sumatriptan (subcutaneous) in acute migraine protocol 1990 (S2B-306)

Co-investigator: sumatriptan (oral) in acute migraine protocol 1990 (S2B-216)

Co-investigator: sumatriptan (oral) in migraine protocol 1991 (S2B-331)

Co-investigator: sumatriptan (oral and subcutaneous) in migraine protocol 1992 (S2B-310)

Principal Investigator: Carnitor and Sodium Valproate in patients with cognitive dysfunction, 1992.

Principal Investigator: DHE vs Sumatriptan in acute migraine 1993 (DHI-703)

Co-investigator: TIND, Safe use of Cognex/Tacrine (THA) 120 mg/day for patients with Alzheimer's Disease 1993.

Principal Investigator: rectal sumatriptan in migraine 1993 (S2B-353)

Co-investigator: TPA in acute stroke 1993.

Principal Investigator: intranasal DHE in familial migraine 1995 (DHE-45)

Co-investigator: STEPS, study of Neurontin: Titration to effect, profile of safety 1995.

Co-investigator: ALERT, Adjunctive Lamictal (Lamotrigine) in Epilepsy and Response to Treatment 1995.

Co-investigator: oral sumatriptan in adolescent migraine (SUMA-2002)

Principal Investigator: subcutaneous sumatriptan in the workplace for migraine (SUMA-4004)

Co-investigator: oral naratriptan in adolescent migraine 1995 (S2WA-3012)

Co-investigator: Baker Norton: Cervene: Modification of outcome in patients with acute ischemic stroke, a double-blind, randomized, placebo-controlled, parallel group, dose comparison study

Co-Investigator: Icos: Phase 2 Study of Hu23F2G in acute exacerbations of multiple sclerosis, 1997.

Co-Investigator: Algos: Morphine with Dextromethorphan versus Morphine in cancer and other
chronic pain, 1997.

Principal Investigator: Hoechst Marion Roussel Protocol VGPR00101: Efficacy of rational polytherapy with Sabril (Vigabatrin) monotherapy in the management of patients with non-refactory complex partial seizures. September 1995.

Co-Investigator: Wyeth-Ayerst Protocol 8997-A1-307-US and 897-A1-312-US: A double-blind safety, tolerance and efficacy study of Zaleplon in adult outpatients with insomnia. September 1995.

Principal Investigator: Cambridge Neuroscience Protocol CNS 1102-008: A multi-center, double-blind, placebo-controlled, dose-finding efficacy study of CNS 1102 in patients with acute cerebral ischemia. June 1995.

Principal Investigator: Parke-Davis Neurontin (STEPS) study for seizure. March 1995.

Principal Investigator: Burroughs-Wellcome Lamictal (ALERT) study for seizure. March 1995.

Principal Investigator: Lorex LES02 Protocol: Assessment of the Efficacy and Safety of Eliprodil in Patients with Acute Ischemic Stroke, June, 1996.

Principal Investigator: Knoll Pharmaceuticals Ancrod: Parallel, Group Sequential Double-Blind,
Randomized, Placebo-Controlled Study of the Safety and Efficacy of IV Ancrod given within 3 hours after the onset of Acute Ischemic Stroke, June, 1996.

Principal Investigator: Boehringer Ingelheim Inc: a Phase 2/3 multi-center, double-blind, placebo-controlled study to evaluate the efficacy, safety, tolerability, and pharmacokinetics of two doses of IV Aptiganel Hydrochloride versus placebo in patients with acute ischemic stroke, 1996.

Principal Investigator: Pfizer/Eisai: An open-label multi-center clinical trial evaluating the safety and efficacy of Donepezil HCL (E2020) in patients with Alzheimer's Disease, 1996.

Principal Investigator: Zeneca: A multi-center, double-blind, randomized comparison of Zolmitriptan and Sumatriptan in the acute treatment of multiple migraine headaches, 1997.

Principal Investigator: Novartis: An open-label study to evaluate the safety and efficacy of 1.5 mg BID of Exelon in patients with mild to severe probable Alzheimer's Disease in the community setting, 1997.

Principal Investigator: Eisai: A 24 week, multi-center, double-blind, placebo-controlled evaluation of the efficacy and safety of Donepezil Hydrochloride (E2020) in patients with dementia associated with cerebrovascular disease, 1997.

Principal Investigator: Pozen: A single dose, double-blind, dose ranging, placebo-controlled safety and efficacy study of various doses of Naproxen Sodium and Metoclopramide in subjects with acute migraine headaches, 1997.

Principal Investigator: GlaxoWellcome: S2WA4003, A randomized double-blind, double dummy, active placebo-controlled, parallel group evaluation of oral Naratriptan (2.5 mg) compared to Oral Naproxen Sodium (275 mg) on Migraine related quality of life, 1997.

Sub Investigator: Icos Phase 2 Study of Hu23F2G in Acute Exacerbation of Multiple Sclerosis, 1997-98.

Principal Investigator: GlaxoWellcome: Open Randomized comparison of Add-on Lamotrigine or Valproate/Carbomazepine Withdrawing to Monotherapy in Patients With Treatment Resistant Epilepsy, 1998.

Sub-Investigator: Berlex: A Double-blind, placebo-controlled multi-center study to evaluate the efficacy and safety of 2 intended doses of intramuscular Phenoxybenzamine Hydrochloride Injection versus placebo in chronic muscle pain, 1998.

Principal Investigator: Parke-Davis: A 5 week, double-blind, placebo-controlled, parallel group study of pregabalin (I 50 and 450 mg/day) in patients with postherpetic neuralgia, 1998.

Principal Investigator: Abbott. The Safety and Efficacy of DivalProex Sodium Extended-Release Tablets in Migraine Prophylaxis: A Double-Blind, Placebo-Controlled Study, 1998.

Sub-Investigator: Targon: A Multi-center, Randomized Double-Blind, Double-Dummy, Parallel Group Study of Morphelan in patients with chronic, moderate to severe pain, 1999.

Principal Investigator: Centaur: A 90 day Safety Study of CPI-1189 in male and female Parkinson's patients on L-Dopa plus Carbidopa, 1999.

Principal Investigator: Janssen: Placebo-controlled evaluation of galantamine in the treatment of Alzheimer's Disease, 1999.

Sub-Investigator: Parke-Davis: Pregabalin add-on trial: A randomized, double-blind, placebo-controlled study in patients with partial seizures, 1999.

Principal Investigator: Pfizer: A multi-center trial to evaluate the efficacy, tolerability and subject satisfaction with Eletriptan in the treatment of migraine headache attacks in Neurology practices, 1999.

Sub-investigator: R.W. Johnson: A randomized, double-blind, parallel group, monotherapy study to compare the safety and efficacy of two doses of Topiramate in the treatment of newly diagnosed or recurrent epilepsy, 1999.

Principal Investigator: R.W. Johnson: A double-blind, placebo-controlled, parallel group, dose response study to evaluate the efficacy and safety of topiramate versus placebo in the relief of pain in diabetic peripheral neuropathy, 1999.

Principal Investigator: GlaxoWellcome: An Open-label Evaluation of the Long-Term Safety or Oral Naratriptan 1 mg Twice Day as Short-Term Prophylactic Treatment for Menstrually-Associated Migraine, 2000.

Principal Investigator: Praecis Pharmaceuticals: A randomized, double-blind, parallel Group Study of the safety and efficacy of Latranal compared to Doxepin Cream and Placebo in patients with chronic low back pain, February 2001.

Principal Investigator: Novartis: Trileptal Diabetic Neuropathy Phase IV study, March 2001.

Principal Investigator: Janssen Research GAL-INT-26 Cerebral Vascular Dementia, August 2001.

Principal Investigator: AstraZeneca Zanadu Zomig ZMT: Open Label Comparison of the Effects of Zomig ZMT and Usual Migraine Care on Work Loss, Productivity, and Patient Preference December 2001.